We are motivated to prepare new iron-sulfur clusters, because these are important biological cofactors that can perform amazing reactions like N₂ and CO₂ reduction, and because they have unusual electronic structures that are a challenge to modern chemistry. In our work, we have prepared numerous unusual clusters and a few of them are shown below.

A current topic of research is iron-nickel-sulfur clusters, which are motivated by the active site of CO dehydrogenase, an enzyme that efficiently interconverts CO₂ and CO. We are exploring the feasibility of unprecedented metal geometries and oxidation states, with the goal of understanding what is possible in the natural system.